Every day, approximately 80 people are diagnosed with Type 1 diabetes.
Type 1 diabetes (juvenile diabetes) is an autoimmune disease that occurs when a person's pancreas makes little to no insulin. The disease develops when the body's immune system attacks and destroys the cells in the pancreas that produce insulin, called beta cells. Without insulin, too much glucose stays in the blood. Over time, increased glucose in the blood can lead to serious problems with the heart, kidneys, nerves, and eyes.
Because the cause of the disease is still unknown, after more than 100 years, we still treat the symptoms of diabetes, rather than the disease itself. Scientists believe that a person's own immune system, directed by genetic and environmental factors, plays a major role in the development of the disease. Before we can develop new treatments and a cure for diabetes, laboratory research is needed to understand the mechanics and triggers of type 1 diabetes.
The Max McGee National Research Center for Juvenile Diabetes is using a genetic approach to try to better understand the step-by-step mechanisms that cause the destruction of the beta cells by studying the family members of people with type 1 diabetes. Blood collected from family members enrolled in the study is analyzed to measure immune responses associated with type 1 diabetes. Your donation will help continue research into the underlying processes that result in type 1 diabetes.
You can help. Just $8.00 will pay for the laboratory supplies needed to process one research volunteer's blood sample.
Make your donation of $5 or more an ongoing gift by checking the "Make this a Monthly Gift" box and you will help researchers find a cure for Type 1 Diabetes, each and every month.
Update from the Field
Donors like you have provided funding that helps facilitate ongoing research efforts. They collected and archived samples from 98 subjects in the first 8 months of 2017. These included Type 1 diabetics, family members, and unrelated healthy controls. Funds from Greater Good most recently helped cover costs of DNA extraction for some subjects.
Donors like you have provided funding that helps facilitate ongoing research efforts. The Max McGee National Research Center for Juvenile Diabetes, together with Childrenâs Hospital of Wisconsin, has a continued focus on the processes and factors contributing to the development of Type 1 Diabetes. Of equal interest are those subjects with high risk for T1D who manage to escape onset. The Max McGee National Research Center had published a new biomarker of pancreatic beta cell death; in mouse and rat diabetes models, as well as in human patients. This may lead to a new method of tracking diabetes development in at-risk patients. They have been able to process additional subjects for storage of plasma and immune cells. These materials are critical to ongoing research studies.
The Max McGee National Research Center for Juvenile Diabetes continues to research the underlying causes of Type 1 Diabetes. Thanks to your generous support, the center has learned a great deal about the immune state in Type 1 diabetes (T1D) and have identified disease progression biomarkers in T1D.
Recent funding has helped process a number of samples from research volunteers, and thereby helped their research faculty to perform their research, publish their findings, and garner additional funding. The Max McGee National Research Center for Juvenile Diabetes is one of many groups working towards a cure. With recent breakthroughs in research, we are one step closer to finding a cure for this devastating disease.
The Max McGee Research Center is associated with Children's Hospital of Wisconsin. Together they are committed to establishing an internationally recognized center for diabetes research. There are many different areas of diabetes research; however, the main focus of this research center will be to find why and how type 1 diabetes occurs.
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